To perform properly the task for which they have been synthesized, proteins must first assemble to form effective cellular ‘machines’. But how do they recognize their partners at the right time? Researchers have deciphered the fundamental role of the Not1 protein, conserved in all eukaryotic organisms: by regulating the activity of ribosomes, Not1 allows proteins that must work together to be synthesized in the same place and at the same time.
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