What’s known as the genome-wide polygenic score, or GPS, combines information from many thousands of genetic markers, each with only a minimal effect, to produce an overall assessment of disease risk based on an individual’s entire genetic background. While a recent publication claimed that the GPS could be used by doctors to identify patients at high risk of conditions such as heart disease, cancer, and diabetes, a new study casts doubt on these claims.
Study questions value of genetic risk scores
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