Researchers have found that RssB — a protein that specifically recognizes a critical stress-response master regulator in bacteria and delivers it to the recycling machinery somewhat like a recycling truck — forms a compact structure with a factor that inhibits RssB activity. The inhibition factor, called IraD, is triggered by DNA damage, one of many stresses the master regulator helps bacteria survive by turning on important genes.
Scientists capture a ‘snapshot’ of bacterial stress-response regulator’s ‘recycling truck’
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