Researchers have developed a computational model for human MEK1, a protein with potential as a drug target for a variety…
Somatic symptom disorder linked to changes in brain functional connectivity
Alterations in functional connectivity of the brain may help in understanding the neurobiological changes leading to somatic symptom disorder (SSD),…
Patent-pending probiotic could disrupt Crohn’s disease biofilms
Probiotics typically aim to rebalance bacteria populations in the gut, but new research suggests they may also help break apart…
Eosinophilic oesophagitis and food allergy
Eosinophilic oesophagitis (EoE) is an allergic condition of the oesophagus. It is a clinico-pathological diagnosis in which intermittent dysphagia and/or…
Gastric tumours
Gastric tumours are subdivided into those of epithelial and stromal origin. Malignant tumours are more common than benign, with adenocarcinomas…
Coeliac disease
Coeliac disease (CD) is a common, chronic, immune-mediated small bowel enteropathy resulting from gluten exposure in genetically susceptible individuals. Considerable…
Disorders of the mouth
Disorders of the mouth, whether as a consequence of primary disorders, systemic disease or treatment, may be encountered across most…
Barrett’s oesophagus and oesophageal adenocarcinoma
Oesophageal adenocarcinoma (OAC) has increased dramatically in Western countries, including the UK, over the past 30 years. It usually presents…
Small bowel transplantation – the latest developments
The UK has played a pivotal role in the development of intestinal transplantation to a procedure that is routinely offered…
New imaging method tested for first time on human patients
A new study could significantly improve methods for detecting and diagnosing congenital heart disease in infants and small children. Researchers…