Treatment with a choline kinase inhibitor prompts immune cells to clear away damaged mitochondria, thus reducing NLRP3 inflammasome activation and…
New imaging technique reveals ‘burst’ of activity before cell death
Using a novel optical imaging technique, researchers discovered connections between the macromolecular structure and dynamic movement of chromatin within eukaryotic…
Broken mitochondria use ‘eat me’ proteins to summon their executioners
When mitochondria become damaged, they avoid causing further problems by signaling cellular proteins to degrade them. In a new study,…
Longer neutrophil lifespan may contribute to HIV-associated intestinal inflammation
The increased survival of white blood cells called neutrophils is associated with alterations in the intestinal microbiome of HIV-infected individuals,…
Case of tick-borne relapsing fever in Mexico
Tick-borne relapsing fever (TBRF) is a recurring fever caused by exposure to infected Borrelia bacteria. Several cases have been reported…
Protein complex may help prevent neurodegenerative diseases
The protein complex NAC in the cell helps to prevent the aggregration of proteins associated with several neurodegenerative diseases.
Mice reveal 38 new genes involved in hearing loss
Multiple new genes involved in hearing loss have been revealed in a large study of mouse mutants. The new genes…
New role for sensory signals in the brain
Learning how to tie a shoe or shoot a basketball isn’t easy, but the brain somehow integrates sensory signals that…
Crucial ‘electrical switch’ in brain
Scientists have revealed the structure of a critical receptor in the brain associated with learning, memory, behavior and mood. The…
Ketamine reverses neural changes underlying depression-related behaviors in mice
Researchers have identified ketamine-induced brain-related changes that are responsible for maintaining the remission of behaviors related to depression in mice.…