Although classical Hodgkin’s lymphoma is generally easily treatable today, many aspects of the disease still remain a mystery. A team has now identified an important signaling molecule in the biology of this lymphoma: LTA. It helps the cancer to grow unimpeded – for example, by activating genes for immune checkpoint ligands that protect tumor cells from the body’s built-in defense system.
Why Hodgkin’s lymphoma cells grow uncontrollably
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