In a landmark study, scientists discovered what makes white blood cell counts spike in individuals who have high cholesterol, possibly leading to new therapies for heart disease. They looked at hypercholesterolemia, which is the type of high cholesterol that causes very high levels of LDL — the so-called ‘bad’ cholesterol — to circulate in the blood. They identified a new regulatory mechanism in zebrafish models responsible for this increase.
Novel insights into cholesterol regulation may lead to new therapies for heart disease
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