Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a new study. These findings have important implications for the opioid epidemic, suggesting that some patients suspected of drug-seeking may in fact be under-medicated and just are seeking more effective pain relief. They also could help explain why some people exceed the prescribed dose of tramadol, increasing their risk of addiction.
Common antidepressants interact with opioid med to lessen pain relief
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