In Western populations, fibromuscular disease accounts for around 10% of all cases of renal artery stenosis (RAS), usually presenting as hypertension in young people, most often women; there is often a successful response to angioplasty. Atherosclerotic renovascular disease (ARVD) accounts for the remaining 90% of cases of RAS. ARVD is a disease of ageing, frequently associated with hypertension and renal dysfunction. It is commonly accompanied by major atherosclerotic vascular disease in other parts of the body, such as coronary artery disease, peripheral vascular disease, cerebrovascular disease and aortic aneurysms.
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