Patients with bowel cancer who have stopped responding to a widely used targeted drug could benefit from immunotherapy, a major new study reveals. Scientists found that bowel tumours which had initially responded to cetuximab before developing resistance became more visible to the immune system — potentially leaving them vulnerable to immunotherapies. A phase II clinical trial has already begun to test the possible benefit of immunotherapy in patients who have stopped responding to cetuximab.
Immunotherapy could work against bowel cancers resistant to important targeted treatment
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