Immune checkpoint inhibitors uses the immune system to fight cancer. But among patients with non-small cell lung cancer (NSCLC) who receive checkpoint inhibitor immunotherapy, recent reports suggest that up to 19% may develop a dangerous complication: an inflammation of their lungs, dubbed checkpoint inhibitor pneumonitis (CIP). Now, researchers have studied the immune cells of NSCLC patients who have CIP and what sets them apart from patients who don’t.
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