Neural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives like bone and tooth-forming cells defies fundamental concepts in developmental and stem cell biology. A research team has found a solution to this mystery by demonstrating an earlier origin of the neural crest in chick embryos.
Embryonic development: Earlier origin of neural crest cells
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