Deletion of the gene that codes for an enzyme called GSTM1 increased kidney injury in mice with hypertension and kidney disease, but supplementing the diet with broccoli powder lessened kidney injury in the genetically altered mice. In humans, high consumption of broccoli and other cruciferous vegetables was linked with a lower risk of kidney failure, primarily in individuals lacking GSTM1.
Genetics may determine who benefits from broccoli’s effects on kidney health
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