Scientists from Australia and the US have discovered and identified the genetic cause of a previously unknown human autoinflammatory disease. The researchers determined that the autoinflammatory disease, which they termed CRIA (cleavage-resistant RIPK1-induced autoinflammatory) syndrome, is caused by a mutation in a critical cell death component called RIPK1. The discovery suggests that compounds that inhibit cell death might be useful in treating autoinflammatory diseases.
New human autoinflammatory disease
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