A research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington’s Disease. Using genetic mouse models, they have discovered that neurons in the striatum, a brain area involved in controlling movement, require the huntingtin gene for regulating the body’s movements, maintaining cell health during aging, and developing functioning connections between cells.
New roles found for Huntington’s disease protein
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