In the bone marrow, blood stem cells via precursor cells give rise to a variety of blood cell types with various functions: white blood cells, red blood cells, or blood platelets. In which cell type a cell develops depends on various factors. The correct dosage of the enzyme MOF at the right time triggers developmental programs in blood stem cells and precursor cells, and the cells differentiate into red blood cells.
Epigenetic mechanisms of blood cell differentiation
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