Acute coronary syndrome induced by a hypersensitivity reaction to allergen exposure is known as Kounis syndrome.1 We present a case of recurrent Kounis syndrome in a patient with coronary artery disease who developed coronary vasospasm following administration of perflutren lipid microsphere (Definity®) echocardiographic contrast, followed by lethal recurrent vasospasm after administration of iodixonal (Visipaque®) angiographic contrast, despite administration of standard contrast allergy prophylaxis.
Recurrent Lethal Allergic Coronary Vasospasm
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