Women live longer than men with Alzheimer’s because their sex chromosomes give them genetic protection from the ravages of the disease. Women get two ‘doses’ of a gene that only exists on the X chromosome. And some people, both male and female, have an especially potent variant of this gene. Long-term studies of older people, many of whom already had mild cognitive impairment, showed women with one or two copies of the variant progressed more slowly toward Alzheimer’s.
Female chromosomes offer resilience to Alzheimer’s
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