Autophagy is an important biological recycling mechanism that influences the progression of aging in animals. Here, age-related changes in autophagy were studied in multiple model organisms. A team found that Rubicon suppression led to reduction of age-associated motor decline, as well as reduction of fibrosis, and that Rubicon could be an important new target for treatments designed to reduce the effects of aging in humans.
The key to increased lifespan? Rubicon alters autophagy in animals during aging
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