The use of primary mesenchymal stem cells (MSCs) is fraught with ageing-related shortfalls such as limited expansion and early senescence. Human induced pluripotent stem cells (iPSCs)-derived MSCs (iMSCs) have been shown to be a useful clinically relevant source of MSCs that circumvent these agiing-associated drawbacks.
Human iPSC-derived MSCs from aged individuals acquire a rejuvenation signature
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