Polygenic risk scores — genetic risk scores that take into account variations in a person’s entire DNA — are able to predict coronary artery disease in those who have not yet had heart attacks. Polygenic risk scores are not as accurate at predicting second heart attacks. With further research and refinement, polygenetic risk scores could help individualize and target lifestyle modifications and therapies aimed at preventing and managing heart disease.
Big picture genetic scoring approach reliably predicts heart disease
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