A preclinical study shows how the interplay of two interleukin signaling proteins, IL-6 and IL-2, affects the development of T follicular helper cells and germinal centers. This interplay may either maintain or disrupt the balancing act of the immune system between attacking infections and benign surveillance of the body’s own cells. Thus, the research may help guide future disease treatment for autoimmune diseases like lupus.
How IL-6 allows the immune response to develop for a key cell, the T follicular helper
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