3D model of human liver for better diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes. Researchers now generated 3D geometrical and functional models of human liver tissue for different disease stages. They reveal new critical tissue alterations, providing new insights into pathophysiology and contributing to high definition medical diagnosis.