Cells infected with HIV make two forms of the virus’s RNA. A new article finds a single nucleotide controls which version of viral RNA an infected cell makes; both forms are necessary for HIV to replicate. The critical nucleotide happens to be in a region of the HIV genome with low mutation rates. That placement makes it a promising target for new therapies, because the virus is less likely to develop resistance.
Breakthrough discovery in HIV research opens path to new, better therapies
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