Covalent cross-links between proteins and DNA are among the most hazardous types of DNA damage. Researchers have now characterized an enzyme that breaks such bonds, and elucidated how it specifically recognizes sites of damage.
DNA repair: Locating and severing lethal links
Covalent cross-links between proteins and DNA are among the most hazardous types of DNA damage. Researchers have now characterized an enzyme that breaks such bonds, and elucidated how it specifically recognizes sites of damage.