Patients with chronic heart failure have a vulnerable myocardial function and are susceptible to electrolyte disturbances. In these patients, diuretic…
Prevalence, Determinants, and Clinical Associations of High-Sensitivity Cardiac Troponin in Patients Attending Emergency Departments
High-sensitivity cardiac troponin assays may improve the diagnosis of myocardial infarction but increase the detection of elevated cardiac troponin in…
Management of Acute Ischemic Stroke
The treatment of acute ischemic stroke has undergone a revolution recently with the publication of five positive thrombectomy trials in…
Annals of Communication: ’Giving a Patient a Diagnosis‘ and Other Idioms in Development
Communication is at the heart of the medical enterprise. We doctors share our research and our interpretations of that research…
Classic Lesion, Not-So-Classic Cause
Calciphylaxis (also known as calcific uremic arteriolopathy) is a serious disorder characterized by skin necrosis secondary to reduction in the…
Genomics and Precision Medicine to Combat Opioid Use Disorder
Chronic pain is a debilitating disorder affecting approximately 100 million people, or almost 30% of the adult population of the…
Canakinumab: Promises and Future in Cardiometabolic Diseases and Malignancy
Inflammation has proven in multiple studies to be responsible for the progression of cardiometabolic diseases and malignancies. The interleukin family…
An Overlooked Cause of Polyuria
A 40-year-old woman presented to the Outpatient Department with complaints of frequent urination and excessive thirst for 3 months. She…
Evidence Basis for a Point-of-Care Ultrasound Examination to Refine Referral for Outpatient Echocardiography
Few data exist on the potential utility of a cardiac point-of-care ultrasound (POCUS) examination in the outpatient setting to assist…
CLIPPERS: An Increasingly Recognized Chronic Inflammatory Central Nervous System Disorder
Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) is a rare chronic inflammatory neurological syndrome affecting multiple…