Sleep duration has been shown to be associated with all-cause mortality; however, its relationship with cause-specific fatal events remains uncertain.…
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Vitamin D Status and Exercise Capacity in Older Patients with Heart Failure with Preserved Ejection Fraction
Background: Older patients with heart failure with preserved ejection fraction have severe exercise intolerance. Vitamin D may play a role…
Role of High-Dose Beta-Blockers in Patients with Heart Failure with Preserved Ejection Fraction and Elevated Heart Rate
Beta-blockers in high target doses are recommended for heart failure with reduced ejection fraction (HFrEF) but not for preserved ejection…
Dementia and Atrial Fibrillation: Pathophysiological Mechanisms and Therapeutic Implications
Atrial fibrillation increases the risk of stroke by a factor of four- to fivefold, and dementia is a common consequence…
The Necessity of Sham Controls
A fundamental issue in biomedical research is how we prove a therapy is effective. When considering medications intended to improve…
After the Match: Cultivating a Community of Support, Retention, and Mentoring to Enhance Diversity
In 2004, the Association of American Medical Colleges defined underrepresented in medicine as “racial and ethnic populations that are underrepresented…
Periprocedural Bridging Anticoagulation: Measuring the Impact of a Clinical Trial on Care Delivery
Use of bridging anticoagulation has been shown to be harmful and without benefit in warfarin-treated patients with atrial fibrillation. We…
Applying Evidence-Based Medicine to Shared Decision Making: Value of Restricted MeanSurvival Time
GJ is a 79-year-old woman with hypertension, diabetes, osteoporosis, depression, and New York Heart Association class II heart failure with…
Recertification: A Tale of Good Intentions but Lots of Strife
The American Board of Internal Medicine (ABIM) is the largest of 24 certifying boards recognized by the American Board of…
Are We Ready to Practice Lifestyle Medicine?
There is no longer any serious doubt that what each of us does in our daily lives profoundly affects our…